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Tailoring Guanosine Hydrogels for Various Functions

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서명/저자사항Tailoring Guanosine Hydrogels for Various Functions.
개인저자Plank, Taylor N.
단체저자명University of Maryland, College Park. Chemistry.
발행사항[S.l.]: University of Maryland, College Park., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항146 p.
기본자료 저록Dissertation Abstracts International 79-11B(E).
Dissertation Abstract International
ISBN9780438158450
학위논문주기Thesis (Ph.D.)--University of Maryland, College Park, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Jeffery T. Davis.
요약Supramolecular hydrogels are of current interest for their ease of use, potential biocompatibility, and reactivity to stimuli. These gel materials have found use in a number of fields ranging from drug delivery and tissue engineering to sensing
요약Modification of the 5'-OH group of G 1 to form 5'-deoxy-5'-iodoguanosine (5'-IG 2) results in a hydrogel that self-destructs via intramolecular cyclization to 5'-deoxy-N3,5'-cycloguanosine (5'-cG 3). Guanine analog drugs can be incorporated int
요약Substitution of boric acid with benzene-1,4-diboronic acid (BDBA 4) to form hydrogels with G 1 and K+ results in hydrogels that can be crosslinked with Mg2+. These G-BDBA-Mg hydrogels have a lower critical gelator concentration (cgc) than their
요약Utilizing binary mixtures of 8-aminoguanosine (8AmG 5) with G 1 allows for the formation of hydrogels with various salts. Hydrogels made of different salts preferentially absorb either cationic or anionic dyes from water, making them candidates
요약Other 8-substituted G-analogs, including, 8-bromoguanosine (8BrG 6), 8-iodoguanosine (8IG 7), and 8-morpholinoguanosine (8morphG 8) can be used in binary mixtures with G 1 to form gels at room temperature upon mixing with KB(OH)4. Room temperat
일반주제명Chemistry.
Organic chemistry.
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