자료유형 | 학위논문 |
---|---|
서명/저자사항 | Tailoring Guanosine Hydrogels for Various Functions. |
개인저자 | Plank, Taylor N. |
단체저자명 | University of Maryland, College Park. Chemistry. |
발행사항 | [S.l.]: University of Maryland, College Park., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 146 p. |
기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
ISBN | 9780438158450 |
학위논문주기 | Thesis (Ph.D.)--University of Maryland, College Park, 2018. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Jeffery T. Davis. |
요약 | Supramolecular hydrogels are of current interest for their ease of use, potential biocompatibility, and reactivity to stimuli. These gel materials have found use in a number of fields ranging from drug delivery and tissue engineering to sensing |
요약 | Modification of the 5'-OH group of G 1 to form 5'-deoxy-5'-iodoguanosine (5'-IG 2) results in a hydrogel that self-destructs via intramolecular cyclization to 5'-deoxy-N3,5'-cycloguanosine (5'-cG 3). Guanine analog drugs can be incorporated int |
요약 | Substitution of boric acid with benzene-1,4-diboronic acid (BDBA 4) to form hydrogels with G 1 and K+ results in hydrogels that can be crosslinked with Mg2+. These G-BDBA-Mg hydrogels have a lower critical gelator concentration (cgc) than their |
요약 | Utilizing binary mixtures of 8-aminoguanosine (8AmG 5) with G 1 allows for the formation of hydrogels with various salts. Hydrogels made of different salts preferentially absorb either cationic or anionic dyes from water, making them candidates |
요약 | Other 8-substituted G-analogs, including, 8-bromoguanosine (8BrG 6), 8-iodoguanosine (8IG 7), and 8-morpholinoguanosine (8morphG 8) can be used in binary mixtures with G 1 to form gels at room temperature upon mixing with KB(OH)4. Room temperat |
일반주제명 | Chemistry. Organic chemistry. |
언어 | 영어 |
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