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Function of Discrete MARTX Toxin Domains in Vibrio vulnificus Intragastric Pathogenesis
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Function of Discrete MARTX Toxin Domains in Vibrio vulnificus Intragastric Pathogenesis. |
| 개인저자 | Gavin, Hannah Elizabeth. |
| 단체저자명 | Northwestern University. Life Sciences. |
| 발행사항 | [S.l.]: Northwestern University., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 238 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
| ISBN | 9780438116313 |
| 학위논문주기 | Thesis (Ph.D.)--Northwestern University, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Karla JF Satchell. |
| 요약 | In 2015, the United States Department of Agriculture (USDA) reported that 1 in 6 Americans fall ill with a foodborne infection annually, resulting in more than 3000 fatalities and an estimated $15 billion in economic burden due to combine |
| 요약 | This study investigates the pathogenic mechanisms of V. vulnificus as mediated by its primary virulence factor, the Multifunctional Autoprocessing Repeats-in-Toxins (MARTX) toxin. The MARTX toxin, product of the rtxA1 gene, has been identified |
| 요약 | We also investigate roles for individual effector domains within the larger repertoire. Each of the five investigated MARTX effector domains exhibit functional redundancy in the ability to disrupt phagocytic activity and intestinal barrier integ |
| 일반주제명 | Microbiology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
