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Structure and Mechanism of Fungal Polysaccharide Monooxygenases

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서명/저자사항Structure and Mechanism of Fungal Polysaccharide Monooxygenases.
개인저자Span, Elise Arielle.
단체저자명University of California, Berkeley. Biophysics.
발행사항[S.l.]: University of California, Berkeley., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항53 p.
기본자료 저록Dissertation Abstracts International 80-01B(E).
Dissertation Abstract International
ISBN9780438324671
학위논문주기Thesis (Ph.D.)--University of California, Berkeley, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Michael A. Marletta.
요약Polysaccharide monooxygenases (PMOs) are a newly discovered and growing superfamily of secreted copper catalysts found in nature. Initial PMO discoveries were made in 2011 describing the role of these enzymes in the cellulolytic machinery of fun
요약Chapter 2 describes a study that probes PMO mechanism in a system utilizing insoluble (and non-quantifiable) cellulose as a substrate. A combination of in vitro assays and electron paramagnetic resonance studies of a panel of single amino acid
요약An example of discoveries that are on the horizon in the PMO field is described in Chapter 3. Genetic experiments and biochemical characterization of a homologously expressed PMO from Neurospora crassa shed light on a new family of PMOs that rep
일반주제명Biochemistry.
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