상세정보
Export to Refworks부가기능
Investigation of Polymer Conjugated Helix Bundle Peptides to Design Micellar Nanocarriers with Tunable Size and Stability using Molecular Dynamics
상세 프로파일
| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Investigation of Polymer Conjugated Helix Bundle Peptides to Design Micellar Nanocarriers with Tunable Size and Stability using Molecular Dynamics. |
| 개인저자 | Ma, Dan. |
| 단체저자명 | Northwestern University. Mechanical Engineering. |
| 발행사항 | [S.l.]: Northwestern University., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 131 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
| ISBN | 9780438125148 |
| 학위논문주기 | Thesis (Ph.D.)--Northwestern University, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Sinan Keten. |
| 요약 | Hybrid polymer-peptide conjugates are receiving increasing attention as a promising class of biomaterials. Polymer conjugated coiled-coil peptides are a new addition to these designer macromolecules. Even though a variety of experiments and comp |
| 요약 | Building on these findings, we focus on a recent design that has utilized end-conjugation of alkyl chains to 3-helix coiled-coils to achieve amphiphilicity, combined with the side-chain conjugation of polyethylene glycol (PEG) to tune micelle si |
| 요약 | Homomeric micelles with tunable size, shape and stability have been extensively studied for biomedical applications such as drug carriers. However, designing the local valency and self-assembled morphology of nanophase-separated multicomponent m |
| 일반주제명 | Mechanical engineering. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
