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Characterization of Rare Genetic Variation in Polycystic Ovary Syndrome
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Characterization of Rare Genetic Variation in Polycystic Ovary Syndrome. |
| 개인저자 | Gorsic, Lidija Kristina. |
| 단체저자명 | Northwestern University. Life Sciences. |
| 발행사항 | [S.l.]: Northwestern University., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 160 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
| ISBN | 9780438117174 |
| 학위논문주기 | Thesis (Ph.D.)--Northwestern University, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Advisers: Ji-Yong Julie Kim |
| 요약 | Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting approximately 1 in 10 reproductive-age women and remains the leading cause of female factor infertility among women of childbearing age. PCOS presents with features of hyp |
| 요약 | Two of the 11 panel genes included anti-Mullerian hormone ( AMH) and its specific type II receptor (AMHR2). Women affected with PCOS often have elevated levels of AMH. In the ovary AMH inhibits follicle maturation, thus the elevated AMH levels s |
| 요약 | Given that PCOS is a complex disorder with a heterogeneous presentation, several genes and pathways likely lead to various PCOS phenotypes. Analyses of targeted resequencing data also identified predicted deleterious missense variants, specific |
| 일반주제명 | Genetics. Endocrinology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
