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Kinetic Studies of Multivalent Nanoparticle Adhesion
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Kinetic Studies of Multivalent Nanoparticle Adhesion. |
| 개인저자 | Wang, Mingqiu. |
| 단체저자명 | University of California, Irvine. Biomedical Engineering - Ph.D.. |
| 발행사항 | [S.l.]: University of California, Irvine., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 147 p. |
| 기본자료 저록 | Dissertation Abstracts International 80-01B(E). Dissertation Abstract International |
| ISBN | 9780438294868 |
| 학위논문주기 | Thesis (Ph.D.)--University of California, Irvine, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Jered Haun. |
| 요약 | Targeted delivery of functional nanoparticles (NPs) holds tremendous potential in diagnostics and therapeutics of vascular diseases and cancer. One of the major attributes is their ability of forming multiple bonds with target cells, thereby pro |
| 요약 | In this work, we first developed Nano adhesive dynamics (NAD) simulation to investigate the binding dynamics between an antibody-conjugated, 210-nm-diameter sphere and an ICAM-1-coated surface. In the NAD simulation, the particle motions are det |
| 요약 | In order to understand the influence of NP bonding heterogeneity on adhesion dynamics, we further examined NP detachment behaviors at higher resolutions: at sub-population level, in which we grouped NPs with similar bonding ability as in one bon |
| 일반주제명 | Biomedical engineering. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
