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Optimal Treatment Design for Chronic Myeloid Leukemia with Multiple Targeted Therapies

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서명/저자사항Optimal Treatment Design for Chronic Myeloid Leukemia with Multiple Targeted Therapies.
개인저자Zhu, Junfeng.
단체저자명University of Minnesota. Industrial and Systems Engineering.
발행사항[S.l.]: University of Minnesota., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항177 p.
기본자료 저록Dissertation Abstracts International 80-01B(E).
Dissertation Abstract International
ISBN9780438353336
학위논문주기Thesis (Ph.D.)--University of Minnesota, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Kevin Leder.
요약A major challenge in understanding tumor growth control is how to model tumor growth and how to design and solve an optimization problem which can provide an efficient treatment. In the dissertation, we aim to develop a mathematical model which
요약However, in clinical application, the outcomes under the optimal protocols are sensitive to variations of parameter settings such as drug effects and the attributes of age, weight, and health conditions in human subjects. One approach to overcom
일반주제명Industrial engineering.
Biomedical engineering.
언어영어
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