자료유형 | 학위논문 |
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서명/저자사항 | Gaining Insights Into the Mitotic Tension Sensing Mechanism in Saccharomyces cerevisiae: Regulation of Chromatin Recruitment of Shugoshin Protein SGO1P. |
개인저자 | Deng, Xiexiong. |
단체저자명 | Michigan State University. Biochemistry and Molecular Biology - Doctor of Philosophy. |
발행사항 | [S.l.]: Michigan State University., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 151 p. |
기본자료 저록 | Dissertation Abstracts International 79-10B(E). Dissertation Abstract International |
ISBN | 9780438023802 |
학위논문주기 | Thesis (Ph.D.)--Michigan State University, 2018. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Min-Hao Kuo. |
요약 | Faithful segregation of chromosomes to progeny cells is essential for species perpetuation. Eukaryotic cells use the spindle assembly checkpoint (SAC) to correct mistakes and prevent chromosome missegregation. SAC ensures that sister chromosomes |
요약 | Genome-wide ChIP-seq assay reveals a unique TSM-dependent, tripartite domain of Sgo1p in each mitotic chromosome. This domain consists of one centromeric and two flanking peaks 3 -- 4 kb away. Strikingly, this trident motif coincides with cohesi |
일반주제명 | Biology. Biochemistry. |
언어 | 영어 |
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