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Resource Competition and the Evolution of Drug Resistance in Malaria Parasites

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서명/저자사항Resource Competition and the Evolution of Drug Resistance in Malaria Parasites.
개인저자Wale, Nina.
단체저자명The Pennsylvania State University. Biology.
발행사항[S.l.]: The Pennsylvania State University., 2016.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2016.
형태사항172 p.
기본자료 저록Dissertation Abstracts International 79-12B(E).
Dissertation Abstract International
ISBN9780438136045
학위논문주기Thesis (Ph.D.)--The Pennsylvania State University, 2016.
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
요약Parasites extract resources from their hosts. Since hosts have little interest in supplying resources to parasites and parasites often live at high densities, resources can be in short supply. As a result, competition between parasites within-ho
요약Here we use a mouse model of malaria infection, Plasmodium chabaudi, to investigate how the availability of within-host resources impacts both the population dynamics of parasites and the emergence of drug resistant parasites. We demonstrate th
요약Our work shows that changes in within-host resource availability can alter parasite-parasite and host-parasite interactions and can be harnessed in the management of drug resistance.
일반주제명Biology.
Evolution & development.
Parasitology.
언어영어
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