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Quantifying and Improving Error Sensitivity of Intensity Modulated Radiation Therapy Quality Assurance

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서명/저자사항Quantifying and Improving Error Sensitivity of Intensity Modulated Radiation Therapy Quality Assurance.
개인저자Steers, Jennifer Mariah.
단체저자명University of California, Los Angeles. Biomedical Physics 0119.
발행사항[S.l.]: University of California, Los Angeles., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항364 p.
기본자료 저록Dissertation Abstracts International 79-10B(E).
Dissertation Abstract International
ISBN9780438021310
학위논문주기Thesis (Ph.D.)--University of California, Los Angeles, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Advisers: Daniel A. Low
요약Purpose: To quantify and elucidate factors affecting error sensitivity in current IMRT QA comparisons performed with the gamma comparison, to investigate causes for gamma comparison insensitivity, and to utilize these results to develop and vali
요약Methods: Over 20,000 gamma comparisons were performed for three detector geometries -- ArcCHECK, MapCHECK, and Delta 4 -- for a variety of IMRT and VMAT cases in the presence of induced errors. Differences in error sensitivity for each device ge
요약Results: Differences in gamma comparison error sensitivity were observed for the ArcCHECK, MapCHECK, and Delta 4 geometries when removing the effects of different spatial sampling for each device. While sensitivity was error type-specific for mo
요약A new method, gradient-dose segmented analysis (GDSA) was developed to allow more clinically meaningful and sensitive IMRT QA comparisons. This method segments the comparison points into regions of high-gradient, high-dose low-gradient, and low-
요약Conclusions: A variety of measurement scenarios were considered in controlled calculation-only comparisons that suggest device-specific and delivery technique-specific gamma criteria may be appropriate in order to achieve similar sensitivity in
일반주제명Nuclear physics and radiation.
Applied physics.
Medicine.
언어영어
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