자료유형 | 학위논문 |
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서명/저자사항 | Differential FOXO1 Localization in SLE and Healthy Human Lymphocyte Subsets. |
개인저자 | Hritzo, Molly K. |
단체저자명 | University of Maryland, Baltimore. Molecular Microbiology and Immunology. |
발행사항 | [S.l.]: University of Maryland, Baltimore., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 161 p. |
기본자료 저록 | Dissertation Abstracts International 80-01B(E). Dissertation Abstract International |
ISBN | 9780438320949 |
학위논문주기 | Thesis (Ph.D.)--University of Maryland, Baltimore, 2018. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Amit Golding. |
요약 | Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease characterized by elevated levels of circulating autoantibodies and multi-organ damage. Although SLE is a highly heterogeneous disease, one factor unifies it: lymphocyte hyp |
요약 | To address this hypothesis, we first developed a method of examining dynamic native FOXO1 localization in human peripheral lymphocyte subsets using imaging flow cytometry (IFC). IFC combines the quantitative power of flow cytometry with the qual |
일반주제명 | Immunology. |
언어 | 영어 |
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