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The Real Option Value of Life And Innovation

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서명/저자사항The Real Option Value of Life And Innovation.
개인저자Li, Meng.
단체저자명University of Washington. Pharmacy.
발행사항[S.l.]: University of Washington., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항99 p.
기본자료 저록Dissertation Abstracts International 79-12B(E).
Dissertation Abstract International
ISBN9780438176782
학위논문주기Thesis (Ph.D.)--University of Washington, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Louis Garrison.
요약Background: Recent developments in healthcare value assessments have expanded the definition of value for medical technologies. The option value of a life-extending treatment is the opportunity of benefiting from future innovations during the ex
요약Methods: In the first study, an interrupted time series analysis was conducted using a large administrative claims database to test whether the utilization of existing treatments changed after the disclosures of the then-investigational drug ipi
요약Results: In the first study, 1,846 metastatic melanoma patients were included. After adjusting for clinical and sociodemographic variables, as well as the underlying time trend, the disclosure of ipilimumab's phase II result was associated with
요약Conclusion: This dissertation research provided the first empirical evidence of the impact of real option value in cancer treatment decision-making. It was also the first to incorporate option value in an ex ante CEA and estimated its potential
일반주제명Pharmaceutical sciences.
언어영어
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