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Boston University Henry M. Goldman School of Dental Medicine

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서명/저자사항Boston University Henry M. Goldman School of Dental Medicine.
개인저자Alwafi, Hanadi A.
단체저자명Boston University. Pediatric Dentistry GSDM.
발행사항[S.l.]: Boston University., 2018.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2018.
형태사항230 p.
기본자료 저록Dissertation Abstracts International 79-10B(E).
Dissertation Abstract International
ISBN9780438041981
학위논문주기Thesis (D.Sc.D.)--Boston University, 2018.
일반주기 Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Laisheng Chou.
요약Background: Thymoquinone (TQ) is one of the most active ingredients of Nigella sativa seed. TQ has a variety of pharmacologic properties including possess antinociceptive, antibacterial, anti-inflammatory, anti-oxidative activities and osteogeni
요약Purpose: This study evaluates the effect of TQ on the attachment efficiency, proliferation, and odontogenic differentiation of Human Dental Pulp Cells (HDPC's). The effect of TQ on odontogenic differentiation was also determined by evaluating al
요약Methods: Human dental pulp cells were cultured in triplicate using growth media with various TQ concentrations: 5 muM, 10muM, 15muM, 30muM, and 10muM as a control group at 7 and 21 days. Crystal violet staining was used to determine cell attachm
요약Results: Higher cell attachment efficiency was shown in all TQ groups at 16 hours (P<. 0001) except for the 5 muM group. A significantly higher cell proliferation rate was shown with low TQ concentration 5 muM at 7 days (P<. 0001) and at 21days
요약Conclusion: All tested TQ concentrations significantly enhanced cell attachment efficiency at 16 hours except TQ =5 muM. Cell proliferation rates were increased significantly by low TQ concentration 5 muM, and decreased significantly with higher
일반주제명Dentistry.
Biology.
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