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Variations in Genes Related to Sleep Patterns in Children with Autism Spectrum Disorder

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서명/저자사항Variations in Genes Related to Sleep Patterns in Children with Autism Spectrum Disorder.
개인저자Johansson, Ann E. E.
단체저자명University of Pittsburgh. Nursing.
발행사항[S.l.]: University of Pittsburgh., 2017.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2017.
형태사항196 p.
기본자료 저록Dissertation Abstracts International 79-12B(E).
Dissertation Abstract International
ISBN9780438364332
학위논문주기Thesis (Ph.D.)--University of Pittsburgh, 2017.
일반주기 Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Advisers: Janice S. Dorman
요약Background: Autism spectrum disorder (ASD) is accompanied by comorbid sleep problems in 40-80% of cases. Previous reports have shown relationships between circadian rhythm genes and sleep problems in ASD. This study aimed to (1) examine relation
요약Methods: This secondary analysis used genotypic and phenotypic data on children aged 4-18- years from the Simons Simplex Collection. An exploratory factor analysis and psychometric evaluation was performed on the Simons Simplex Collection Sleep
요약Results: Approximately 41% of children were categorized as having sleep problems. In the full sample, and in age subgroups, GID and age were the variables most frequently associated with composite sleep problems, Nighttime problems, Daytime pro
요약Conclusions: This study advances our understanding of sleep in ASD by showing that GID, NVIQ, age, sex, and seizures increased the odds of sleep problems
일반주제명Nursing.
언어영어
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