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Characterization of Equine Metabolic Syndrome and Mapping of Candidate Genetic Loci
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Characterization of Equine Metabolic Syndrome and Mapping of Candidate Genetic Loci. |
| 개인저자 | Schultz, Nichol Elizabeth. |
| 단체저자명 | University of Minnesota. Comparative and Molecular Biosciences. |
| 발행사항 | [S.l.]: University of Minnesota., 2016. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2016. |
| 형태사항 | 375 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-10B(E). Dissertation Abstract International |
| ISBN | 9780438030572 |
| 학위논문주기 | Thesis (Ph.D.)--University of Minnesota, 2016. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Advisers: James R. Mickelson |
| 요약 | Equine metabolic syndrome (EMS) is a clustering of clinical signs associated with increased risk of laminitis, a potentially life-threatening condition of the foot. Similar to human metabolic syndrome (MetS), generalized and/or regional adiposit |
| 요약 | Chapter 2 details the largest-ever epidemiological investigation of EMS in which 11 metabolic traits were measured in >600 horses and ponies from 166 farms. The use of multivariate, multilevel regression modeling allowed, for the first time, qua |
| 요약 | Differences in the incretin response may also contribute to individual trait variation. The incretin response, defined as the difference in insulinemic responses between an oral and intravenous glucose challenge, is controlled by intestinal secr |
| 요약 | In Chapter 4, an improved linear mixed model for mapping polygenic traits in a population with familial relationships similar to that in many equine GWAS was developed and validated. The model incorporates a Bayesian variable selection method to |
| 일반주제명 | Genetics. Animal diseases. Statistics. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
