자료유형 | 학위논문 |
---|---|
서명/저자사항 | The Paracrine Function of Smooth Muscle Cells in Vascular Injury and Repair. |
개인저자 | Ren, Jun. |
단체저자명 | The University of Wisconsin - Madison. Endocrinol-Reprod Physiol - AG. |
발행사항 | [S.l.]: The University of Wisconsin - Madison., 2016. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2016. |
형태사항 | 269 p. |
기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
ISBN | 9780438159426 |
학위논문주기 | Thesis (Ph.D.)--The University of Wisconsin - Madison, 2016. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Bo Liu. |
요약 | Vascular smooth muscle cells (SMCs) play a critical role in vascular pathogenesis including intimal hyperplasia (IH), atherosclerosis, and aneurysms. It is generally believed that SMCs respond to vascular injury with apoptosis, loss of contracti |
요약 | In my thesis work, I utilized an apoptotic mediator protein kinase C-delta (PKCdelta) to stress SMCs. The thesis is organized into five chapters. In Chapter 1, I provide a brief review of the accumulating knowledge regarding vascular injury resp |
요약 | In sum, data generated through my dissertation provide experimental proof that stressed SMCs communicate with other cell types through PKCdelta-mediated paracrine signals after vascular injury. These paracrine signals released by stressed SMCs h |
일반주제명 | Biology. Cellular biology. Molecular biology. |
언어 | 영어 |
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: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |