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The Paracrine Function of Smooth Muscle Cells in Vascular Injury and Repair

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서명/저자사항The Paracrine Function of Smooth Muscle Cells in Vascular Injury and Repair.
개인저자Ren, Jun.
단체저자명The University of Wisconsin - Madison. Endocrinol-Reprod Physiol - AG.
발행사항[S.l.]: The University of Wisconsin - Madison., 2016.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2016.
형태사항269 p.
기본자료 저록Dissertation Abstracts International 79-11B(E).
Dissertation Abstract International
ISBN9780438159426
학위논문주기Thesis (Ph.D.)--The University of Wisconsin - Madison, 2016.
일반주기 Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
Adviser: Bo Liu.
요약Vascular smooth muscle cells (SMCs) play a critical role in vascular pathogenesis including intimal hyperplasia (IH), atherosclerosis, and aneurysms. It is generally believed that SMCs respond to vascular injury with apoptosis, loss of contracti
요약In my thesis work, I utilized an apoptotic mediator protein kinase C-delta (PKCdelta) to stress SMCs. The thesis is organized into five chapters. In Chapter 1, I provide a brief review of the accumulating knowledge regarding vascular injury resp
요약In sum, data generated through my dissertation provide experimental proof that stressed SMCs communicate with other cell types through PKCdelta-mediated paracrine signals after vascular injury. These paracrine signals released by stressed SMCs h
일반주제명Biology.
Cellular biology.
Molecular biology.
언어영어
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