자료유형 | 학위논문 |
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서명/저자사항 | Mesoporous Silica Nanoparticles to Target Motoneurons. |
개인저자 | Gonzalez Porras, Maria A. |
단체저자명 | College of Medicine - Mayo Clinic. Biomedical Engineering. |
발행사항 | [S.l.]: College of Medicine - Mayo Clinic., 2017. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2017. |
형태사항 | 225 p. |
기본자료 저록 | Dissertation Abstracts International 80-01B(E). Dissertation Abstract International |
ISBN | 9780438313231 |
학위논문주기 | Thesis (Ph.D.)--College of Medicine - Mayo Clinic, 2017. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 80-01(E), Section: B.
Adviser: Carlos B. Mantilla. |
요약 | Drug delivery systems to motoneurons are critical in developing effective and safe treatments for motoneuron diseases (e.g. amyotrophic lateral sclerosis), as well as in understanding causes of muscle denervation (e.g. spinal cord injury, or age |
요약 | The use of nanoparticles to target the delivery of drugs can potentially ameliorate a number of problems exhibited by conventional 'free' drugs, including poor solubility, limited stability, rapid clearing, and, in particular, lack of selectivit |
일반주제명 | Physiology. Nanoscience. |
언어 | 영어 |
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