자료유형 | 단행본 |
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서명/저자사항 | The "Calcium Paradox" and its Impact on Neurological and Psychiatric Diseases/ Leandro Bueno Bergantin and Afonso Caricati-Neto. [electronic resource]. |
개인저자 | Bergantin, Leandro Bueno,author. Caricati-Neto, Afonso,author, |
판사항 | Second edition. |
발행사항 | Newcastle upon Tyne: Cambridge Scholars Publishing, 2018. |
형태사항 | 1 online resource. |
ISBN | 9781527518346 1527518345 |
내용주기 | Intro; Table of Contents; List of Figures; List of Tables; Preface; Acknowledgements; List of Main Abbreviations; Chapter One; Chapter Two; Chapter Three; Chapter Four; Chapter Five; 5.1 Current therapies to treat neurological and psychiatric diseases; 5.1.1 Alzheimer's disease; 5.1.2 Parkinson's disease; 5.1.3 Depression; 5.1.4 Amyotrophic lateral sclerosis (ALS); 5.1.5 Huntington's disease (HD); 5.1.6 Spinal muscular atrophy (SMA); 5.1.7 Vascular dementia (VD); Chapter Six; Chapter Seven; Chapter Eight; 8.1 Ca2+ Signalling in Healthy Brains, and the Effects of Aging 8.2 Amyloid -Peptide endorses Ca2+ Influx and a Ca2+- Mediated Excitotoxicity8.2.1 Presenilins; 8.3 Cytoskeletal pathology in AD and Ca2+; 8.4 Ca2+ Actions Upstream of the Amyloidogenesis; 8.5 Synapses and Ca2+; 8.6 Selectivity of the Neuronal Vulnerability in AD and Ca2+; 8.7 Improving Neuronal Ca2+ Homeostasis as a Therapeutic Approach for AD; 8.8 Reasonable mechanisms for healthy brain aging and AD; Chapter Nine; Chapter Ten; Chapter Eleven; Bibliography; About the Authors |
요약 | This book extends the original concept of the ""calcium paradox"" discovery, herein compiling more than 300 references in the field of calcium ion (Ca2+/cAMP) signalling pathways, neurotransmission and neurodegeneration, and neurological and psychiatric diseases. In this second edition, novel illustrations and tables (highlighting current medicines for treating these diseases, including their mechanism of action) offer improved insights into the concepts for students and clinicians. The description of other neurodegenerative diseases (Spinal muscular atrophy, Amyotrophic Lateral Sclerosis and. |
일반주제명 | Nervous system --Diseases --Pathophysiology. Calcium channels. HEALTH & FITNESS / Diseases / General. MEDICAL / Clinical Medicine. MEDICAL / Diseases. MEDICAL / Evidence-Based Medicine. MEDICAL / Internal Medicine. |
언어 | 영어 |
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