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Understanding the Consequences of Oncogenic FGFR Mutations on Drug Resistance, Signaling, and Tumorigenic Potential
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Understanding the Consequences of Oncogenic FGFR Mutations on Drug Resistance, Signaling, and Tumorigenic Potential. |
| 개인저자 | Ryan, Molly Rose. |
| 단체저자명 | Yale University. |
| 발행사항 | [S.l.]: Yale University., 2019. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2019. |
| 형태사항 | 163 p. |
| 기본자료 저록 | Dissertations Abstracts International 81-01B. Dissertation Abstract International |
| ISBN | 9781392328682 |
| 학위논문주기 | Thesis (Ph.D.)--Yale University, 2019. |
| 일반주기 |
Source: Dissertations Abstracts International, Volume: 81-01, Section: B.
Publisher info.: Dissertation/Thesis. Advisor: Anderson, Karen S. |
| 이용제한사항 | This item must not be added to any third party search indexes.This item must not be sold to any third party vendors. |
| 요약 | Fibroblast growth factor receptor 1 (FGFR1) has been implicated in numerous cancer types including squamous cell lung cancer, a subset of non-small cell lung cancer (NSCLC) with a dismal 5-year survival rate. Small molecule inhibitors targeting FGFR 1 are currently in clinical trials, with AZD454 7 being one of the furthest advanced |
| 일반주제명 | Pharmacology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
