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Discovering Genetic Drivers in Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Discovering Genetic Drivers in Acute Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation. |
| 개인저자 | Huang, Hu. |
| 단체저자명 | University of Minnesota. Biomedical Informatics and Computational Biology. |
| 발행사항 | [S.l.]: University of Minnesota., 2019. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2019. |
| 형태사항 | 144 p. |
| 기본자료 저록 | Dissertations Abstracts International 81-02B. Dissertation Abstract International |
| ISBN | 9781085574785 |
| 학위논문주기 | Thesis (Ph.D.)--University of Minnesota, 2019. |
| 일반주기 |
Source: Dissertations Abstracts International, Volume: 81-02, Section: B.
Includes supplementary digital materials. Advisor: Kennedy, Caleb |
| 이용제한사항 | This item must not be sold to any third party vendors. |
| 요약 | Acute graft-versus-host disease (GVHD) is one of the major complications after allogeneic hematopoietic stem cell transplantation (allo-HCT) that cause non-relapse morbidity and mortality. Although the increasing matching rate of the human leukocyte antigen (HLA) genes between donor and recipient (DR) has significantly reduced the risk of GVHD, clinically significant GVHD remains as a transplantation challenge, even in HLA-identical transplants. Candidate gene studies and genome-wide association studies have revealed susceptible individual genes and gene pairs from DR pairs that are associated with acute GVHD |
| 일반주제명 | Bioinformatics. Computer science. Immunology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
