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Antiretroviral (ART) and Prevention of Mother-to-Child Transmission (PMTCT) Therapies Adherence in Greater Gaborone, Botswana: A Mixed Methods Health Geographic Study

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서명/저자사항Antiretroviral (ART) and Prevention of Mother-to-Child Transmission (PMTCT) Therapies Adherence in Greater Gaborone, Botswana: A Mixed Methods Health Geographic Study.
개인저자Kelepile, Matlhogonolo.
단체저자명Michigan State University. Geography - Doctor of Philosophy.
발행사항[S.l.]: Michigan State University., 2019.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2019.
형태사항186 p.
기본자료 저록Dissertations Abstracts International 81-03B.
Dissertation Abstract International
ISBN9781085674232
학위논문주기Thesis (Ph.D.)--Michigan State University, 2019.
일반주기 Source: Dissertations Abstracts International, Volume: 81-03, Section: B.
Advisor: Grady, Sue .
이용제한사항This item must not be sold to any third party vendors.
요약Botswana is among the highest HIV/AIDS epidemic burden bearing countries in the world. While treatment for HIV was introduced in Botswana in 2002, the uptake and adherence of the antiretroviral (ART) and Prevention of Mother-to-Child Transmission (PMTCT) therapies are still relatively low. The goal of this research is to provide recommendations on how to improve adherence to ART and PMTCT treatment regimens for adult men and women, and pregnant women and new mothers living with HIV in Botswana. With improved ART adherence, there is high potential for a reduction in new HIV infections as a result of suppressed viral load. This reduction will contribute to the global goal of the UNAIDS (United Nations AIDS) "Treat All Program" to eliminate new HIV infections by 2030. ART adherence is measured in two ways (a) biological (serum CD4 count and viral load) and (b) using a composite score of biological and behavior, including reporting missed dosages. With this in mind, this study will examine three dimensions of ART non-adherence in a sampled population of HIV infected adult men (n = 239) and women (n = 419), including pregnant women or new mothers (n = 67) attending 21 ART clinics in Greater Gaborone. First, ART adherence was investigated at the individual-level to assess and evaluate differences by gender, age and geography. Second, PMTCT was investigated at the individual-level to identify challenges to adherence during pregnancy and early motherhood. Third, the climate of Botswana is hot, arid and dry and this study therefore, investigate the impacts of weather extremes on adherence behavior. The findings from this study show that men have lower adherence to ART than women
일반주제명Geography.
Health sciences.
African studies.
Virology.
언어영어
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