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Essays in Causal Inference: Addressing Bias in Observational and Randomized Studies through Analysis and Design
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Essays in Causal Inference: Addressing Bias in Observational and Randomized Studies through Analysis and Design. |
| 개인저자 | Hasegawa, Raiden B. |
| 단체저자명 | University of Pennsylvania. Statistics. |
| 발행사항 | [S.l.]: University of Pennsylvania., 2019. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2019. |
| 형태사항 | 176 p. |
| 기본자료 저록 | Dissertations Abstracts International 81-02B. Dissertation Abstract International |
| ISBN | 9781085576895 |
| 학위논문주기 | Thesis (Ph.D.)--University of Pennsylvania, 2019. |
| 일반주기 |
Source: Dissertations Abstracts International, Volume: 81-02, Section: B.
Advisor: Small, Dylan S. |
| 이용제한사항 | This item must not be sold to any third party vendors.This item must not be sold to any third party vendors. |
| 요약 | In observational studies, identifying assumptions may fail, often quietly and without notice, leading to biased causal estimates. Although less of a concern in randomized trials where treatment is assigned at random, bias may still enter the equation through other means. This dissertation has three parts, each developing new methods to address a particular pattern or source of bias in the setting being studied. In the first part, we extend the conventional sensitivity analysis methods for observational studies to better address patterns of heterogeneous confounding in matched-pair designs. We illustrate our method with two sibling studies on the impact of schooling on earnings, where the presence of unmeasured, heterogeneous ability bias is of material concern. The second part develops a modified difference-in-difference design for comparative interrupted time series studies. The method permits partial identification of causal effects when the parallel trends assumption is violated by an interaction between group and history. The method is applied to a study of the repeal of Missouri's permit-to-purchase handgun law and its effect on firearm homicide rates. In the final part, we present a study design to identify vaccine efficacy in randomized control trials when there is no gold standard case definition. Our approach augments a two-arm randomized trial with natural variation of a genetic trait to produce a factorial experiment. The method is motivated by the inexact case definition of clinical malaria. |
| 일반주제명 | Statistics. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
