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Use of the Sepsis Bundle in Hospital-onset and Community-onset Sepsis and Effects of Lack of Insurance in Community-onset Sepsis

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서명/저자사항Use of the Sepsis Bundle in Hospital-onset and Community-onset Sepsis and Effects of Lack of Insurance in Community-onset Sepsis.
개인저자Baghdadi, Jonathan.
단체저자명University of California, Los Angeles. Health Policy and Management 007I.
발행사항[S.l.]: University of California, Los Angeles., 2019.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2019.
형태사항111 p.
기본자료 저록Dissertations Abstracts International 81-06B.
Dissertation Abstract International
ISBN9781392477601
학위논문주기Thesis (Ph.D.)--University of California, Los Angeles, 2019.
일반주기 Source: Dissertations Abstracts International, Volume: 81-06, Section: B.
Advisor: Brook, Robert H
이용제한사항This item must not be sold to any third party vendors.
요약Problem: Hospital-onset sepsis is understudied and was not considered in the development and implementation of Centers for Medicare and Medicaid Services (CMMS) core quality measure related to sepsis, SEP-1.Methods: Samples of patients with sepsis were identified by diagnosis codes from the electronic health records of 4 university hospitals and publicly available administrative data from the California Department of Public Health. Multilevel models with random effects were used to evaluate for an association between risk factors and outcomes of interest. Endogenous treatment effects models were used to estimate treatment effects from observational data.Findings: Providers are about 3-times less likely to deliver SEP-1-adherent care for patients with hospital-onset sepsis than patients with community-onset sepsis. The care bundle outlined in SEP-1 was not associated with a treatment benefit (reduced mortality, decreased requirement for vasopressors) in the total sample of eligible patients, in the cohort with community-onset sepsis, or in the cohort with hospital-onset sepsis. However, multiple components of the bundle appeared to improve outcomes in patients with community-onset sepsis. Only the use of antibiotics was associated with reduced mortality in patients with hospital-onset sepsis.Meaning: Hospital-onset and community-onset sepsis are distinct clinical entities-they are managed differently by providers and respond differently to SEP-1-adherent care. Low levels of adherence to the SEP-1 core quality measure for patients with hospital-onset sepsis may not represent a quality gap. Rather, consideration should be given to excluding patients with hospital-onset sepsis from the core quality measure.
일반주제명Medicine.
Public health.
언어영어
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