상세정보
Export to Refworks부가기능
Relationships Between Domain-Specific Cognition and Regional Brain Structure in a Typically Developing Cohort
상세 프로파일
| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Relationships Between Domain-Specific Cognition and Regional Brain Structure in a Typically Developing Cohort. |
| 개인저자 | Curley, Lauren Butler. |
| 단체저자명 | University of California, San Diego. Cognitive Science. |
| 발행사항 | [S.l.]: University of California, San Diego., 2019. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2019. |
| 형태사항 | 226 p. |
| 기본자료 저록 | Dissertations Abstracts International 81-05B. Dissertation Abstract International |
| ISBN | 9781088325599 |
| 학위논문주기 | Thesis (Ph.D.)--University of California, San Diego, 2019. |
| 일반주기 |
Source: Dissertations Abstracts International, Volume: 81-05, Section: B.
Advisor: Jernigan, Terry L. |
| 이용제한사항 | This item must not be sold to any third party vendors. |
| 요약 | Human development is a dynamic, protracted process influenced by genetics, the environment, experience, and many other factors. During development, an individual develops an entirely unique neural architecture along with a unique set of cognitive skills and abilities. Through recent large-scale pediatric neuroimaging initiatives, we now have a better understanding of the protracted structural changes occurring in the developing brain. We are also beginning to map out relationships between developing brain structure and domain-specific cognition, although we haven't fully characterized these relationships and their variability throughout typical development. The goal of this work is to assess how individual differences in regional cortical and subcortical brain structure are related to behavioral and cognitive variability in different domains during childhood and adolescence, which is a period of rapid dynamic change. This work also aims to investigate overlapping as well as distinguishing characteristics of the relationships between developing neural systems and domain-specific cognition. In this dissertation, I focus on three cognitive domains: phonological awareness, spatial working memory, and response inhibition. These three cognitive domains are thought to involve relatively distinct brain regions and networks, allowing us to investigate the specificity of associations between structure and function in the developing brain. In addition, these three domains have been well studied in pediatric, clinical, and adult populations in behavioral and functional neuroimaging studies, leading to relatively well-defined region-specific hypotheses. Utilizing three distinct cognitive domains also supports the investigation of domain-general aspects of cognitive development, such as latent factors or skills supporting multiple areas of cognitive development. In addition, studying multiple cognitive domains allows me to study the reflection of any shared features in the neural architecture. I will first address the region-specific associations between cortical and white matter regions thought to be principally related to each cognitive domain. Following that, I will carry out a more data-driven analysis aimed at exploring possible latent factors underlying the associations between these cognitive domains and structural regions. These results may provide insight into the neurobiological correlates of cognitive development and the nature of individual difference variability during development. |
| 일반주제명 | Neurosciences. Brain research. Cognition & reasoning. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
