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The emerging field of human neural organoids, transplants, and chimeras science, ethics, and governance
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| 자료유형 | 단행본 |
|---|---|
| 서명/저자사항 | The emerging field of human neural organoids, transplants, and chimeras : science, ethics, and governance/ Committee on Ethical, Legal, and Regulatory Issues Associated with Neural Chimeras and Organoids; Committee on Science, Technology, and Law; Policy and Global Affairs; National Academies of Sciences, Engineering, Medicine. |
| 단체저자명 | National Academies of Sciences, Engineering, and Medicine (U.S.). Committee on Ethical, Legal, and Regulatory Issues Associated with Neural Chimeras and Organoids,author. National Academies of Sciences, Engineering, and Medicine (U.S.). Committee on Science, Technology, and Law.issuing body. |
| 형태사항 | 1 online resource (1 PDF file (xvi, 136 pages)): illustrations. |
| 총서사항 | Consensus study report of the National Academies of Sciences, Engineering, Medicine |
| 기타형태 저록 | Print version: 9780309303361 0309303362 |
| ISBN | 9780309304085 0309304083 |
| 서지주기 | Includes bibliographical references. |
| 내용주기 | Front Matter -- Summary -- 1. Introduction -- 2. The Science of Human Neural Organoids, Transplants, and Chimeras -- 3. Ethical Concerns -- 4. Oversight and Governance -- 5. Public Engagement -- 6. Findings of the Committee -- References -- Appendix A: Biographies of Committee and Staff Members -- Appendix B: Committee Meeting Agendas. |
| 요약 | Each year, tens of millions of individuals in the U.S. suffer from neurological and psychiatric disorders including neurodegenerative diseases such as Alzheimer's Disease and Parkinson's Disease, and psychiatric disorders such as autism spectrum disorder, depression and schizophrenia. Treatments for these diseases are often completely lacking or only partially effective, due in large part to the difficulty of conducting brain research and the complexity of the brain itself. Researchers in recent years have developed new models to better represent and study the human brain. The three models considered in this report, all of which generate and use pluripotent stem cells from healthy individuals and patients, are human neural organoids, human neural transplants, and human-animal neural chimeras. The Emerging Field of Human Neural Organoids, Transplants, and Chimeras: Science, Ethics, and Governance reviews the status of research, considers its benefits and risks, discusses associated ethical issues, and considers governance mechanisms for this type of research. |
| 기금정보주기 | This activity was supported by contracts from the National Institutes of Health (Sponsor Award Number HHSN263201800029I/75N98019F00861) and The Dana Foundation. This Project has been funded in whole or in part with federal funds from the National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN263201800029I. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project. |
| 주제명(지명) | United States |
| 일반주제명 | Neurophysiology. Tissues. Transplantation of organs, tissues, etc. Chimerism. Medical ethics. Medical genetics. Brain --Diseases --Alternative treatment. Cell organelles. Intracerebral transplantation. Brain Diseases --therapy Chimerism Organoids Brain Tissue Transplantation Biomedical Research Ethics, Medical Neurophysiology Genetics, Medical Neurophysiologie. Tissus (Histologie) Greffe (Chirurgie) E?thique me?dicale. Ge?ne?tique me?dicale. Cerveau --Maladies --Me?decines paralle?les. Ge?nes chime?res. Organoi?des. Greffes intrace?re?brales. Chimerism. Medical ethics. Medical genetics. Neurophysiology. Tissues. Transplantation of organs, tissues, etc. |
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