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Bioprocessing of Viral Vaccines
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| 자료유형 | 단행본 |
|---|---|
| 서명/저자사항 | Bioprocessing of Viral Vaccines. |
| 개인저자 | Kamen, Amine, Cervera, Laura, |
| 형태사항 | 1 online resource (viii, 320 pages). |
| 기타형태 저록 | Print version: 9781032132112 |
| ISBN | 9781003229797 1003229794 9781000643022 1000643026 1000643050 9781000643053 |
| 기타표준부호 | 10.1201/9781003229797doi |
| 내용주기 | ContentsEditors--List of abbreviations--Chapter 1 Bioprocessing of viral vaccines-Introduction--Amine Kamen and Laura CerveraChapter 2 Introduction to virology--Shantoshini DashChapter 3 Introduction to basic immunology and vaccine design--Alaka Mullick and Shantoshini DashChapter 4 Cell lines for vaccine production--Isabelle Knott, Jean-Philippe Matheise, Isabelle Ernest, and Jean-Pol CassartChapter 5 Upstream processing for viral vaccines-General aspects--Lars Pelz, Sven Go?bel, Karim Jaen, Udo Reichl, and Yvonne GenzelChapter 6 Upstream processing for viral vaccines-Processintensification--Sven Go?bel, Lars Pelz, Udo Reichl, and Yvonne GenzelChapter 7 Downstream processing of viral-based vaccines--Rita P. Fernandes, Cristina Peixoto, and Piergiuseppe NestolaChapter 8 Analytics and virus production processes--Emma PetiotChapter 9 Manufacturing of seasonal and pandemic influenzavaccines-A case study--Cristina A. T. Silva, Shantoshini Dash, and Amine KamenChapter 10 Recombinant vaccines: Gag-based VLPs--Laura Cervera, Irene Gonza?lez-Domi?nguez, Jesu?s Lavado-Garci?a, and Francesc Go?diaChapter 11 Vectored vaccines--Zeyu Yang, Kumar Subramaniam, and Amine KamenChapter 12 Design and production of vaccines against COVID-19using established vaccine platforms--Ryan Kligman, Jesu?s Lavado-Garci?a, and Amine KamenIndex-- |
| 요약 | This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines. Bioprocessing of Viral Vaccines, will provide an overview of the advanced strategies needed to respond to the challenges of new and established viral infection diseases. The first few chapters cover the basics of virology and immunology as essential concepts to understand the function and design of viral vaccines. The core of the content is dedicated to process development, including upstream processing and cell culture of viral vaccines, downstream processing, and extensive analytical technologies specific to viral vaccines. Advanced process analytical technologies (PAT) and Quality by Design (QbD) concepts are also introduced in the context of vaccine manufacturing. The case studies included cover inactivated, attenuated vaccines exemplified by influenza vaccines, sub-unit vaccines exemplified by Virus Like Particles (VLPs: HPV vaccines) and sub-unit vaccines (Flublock), vectored vaccines: adenoviruses and Vesicular stomatitis Virus (VSV) vectored vaccines, genomic vaccines (DNA and mRNA) vaccines as developed for COVID-19 response in particular and a review of COVID-19 vaccines approved or in advanced clinical trials. This book is aimed at graduate engineers and professionals in the fields of vaccinology, bioprocessing, and biomanufacturing of viral vaccines. |
| 일반주제명 | Viral vaccines --Biotechnology. Vaccines. MEDICAL / Biotechnology MEDICAL / Immunology SCIENCE / Biotechnology Vaccines. |
| 언어 | 영어 |
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