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Subtypes of Rumination Associated with White Matter Integrity in Women with Depression
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Subtypes of Rumination Associated with White Matter Integrity in Women with Depression. |
| 개인저자 | Satyshur, Maureen Doyle. |
| 단체저자명 | Northwestern University. Clinical Psychology. |
| 발행사항 | [S.l.]: Northwestern University., 2019. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2019. |
| 형태사항 | 57 p. |
| 기본자료 저록 | Dissertations Abstracts International 81-04B. Dissertation Abstract International |
| ISBN | 9781088332429 |
| 학위논문주기 | Thesis (Ph.D.)--Northwestern University, 2019. |
| 일반주기 |
Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
Advisor: Gollan, Jacqueline K. |
| 이용제한사항 | This item must not be sold to any third party vendors. |
| 요약 | Recent studies have begun to examine white matter connectivity aberrations in psychiatric populations, such as major depressive disorder. Several studies have found reduced white matter integrity (WMI) in depressed samples, though the location of this reduction is not clear. Incorporating symptom measures of depression severity and rumination may allow for increased identification and localization of aberrant WMI in this heterogeneous disorder. This study examined WMI, specifically fractional anisotropy (FA), using diffusion tensor imaging in a sample of depressed adult women (N=45). The relationship between depression severity and subscales of rumination with fractional anisotropy in six tracts were analyzed, including the bilateral superior longitudinal fasciculus, bilateral uncinate fasciculus, and bilateral cingulum bundle. Increased reflective rumination was associated with increased FA in the right cingulum bundle and left uncinate fasciculus. Additionally, post-hoc analyses considered other measures of WMI in those two tracts. Results found that depression rumination and brooding rumination were associated with aberrant WMI in the left uncinate fasciculus. Findings from this study offer a unique understanding of how white matter integrity in prefrontal, temporal, and limbic regions may be associated with different forms of rumination in women diagnosed with major depression. |
| 일반주제명 | Clinical psychology. Neurosciences. Psychology. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
