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Enabling novel treatments for nervous system disorders by improving methods for traversing the blood-brain barrier : proceedings of a workshop

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서명/저자사항Enabling novel treatments for nervous system disorders by improving methods for traversing the blood-brain barrier : proceedings of a workshop/ Lisa Bain, Noam I. Keren, and Clare Stroud, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Health and Medicine Division, the National Academies of Sciences, Engineering, Medicine.
개인저자Bain, Lisa J.,rapporteur.
Keren, Noam I.,rapporteur,
Stroud, Clare,rapporteur,
단체저자명National Academies of Sciences, Engineering, and Medicine (U.S.). Forum on Neuroscience and Nervous System Disorders,issuing body.
발행사항Washington, DC: the National Academies Press, [2018].
형태사항1 online resource (xii, 59 pages): color illustrations.
기타형태 저록Print version: Bain, Lisa J. Enabling novel treatments for nervous system disorders by improving methods for traversing the blood짭brain barrier Washington, D.C. : National Academies Press, [2018] 9780309473071
ISBN9780309473088
030947308X
9780309473101
0309473101


기타표준부호10.17226/25044doi
서지주기Includes bibliographical references (pages 41-44).
내용주기Introduction and overview --Traversing the blood-brain barrier : challenges and opportunities -- Modalities and technologies for brain delivery -- Regulatory considerations for drugs that traverse the blood-brain barrier -- Accelerating research and clinical translation : consortia and public-private partnerships -- Appendixes
요약"Despite substantial advances in developing treatments for the serious illnesses that affect people worldwide, there remains a tremendous unmet need in the treatment of complex neurologic diseases, including neuropsychiatric and neurodegenerative disorders. Chief among the challenges that have hindered the development of therapeutics for central nervous system (CNS) disorders is the blood-brain barrier (BBB). The Forum on Neuroscience and Nervous System Disorders of the National Academies of Sciences, Engineering, and Medicine convened a workshop to explore the challenges associated with the BBB that have thus far stymied development of CNS drugs, examine new technologies that could address these challenges, and highlight potential opportunities for moving the field forward. This publication summarizes the presentations and discussions from the workshop"--Publisher's description.
회의명Enabling Novel Treatments for Nervous System Disorders by Improving Methods for Traversing the Blood-Brain Barrier (Workshop) (2017 : Washington, D.C.),
일반주제명Nervous system --Diseases --Treatment --Congresses.
Blood-brain barrier --Congresses.
HEALTH & FITNESS / Diseases / General
MEDICAL / Clinical Medicine
MEDICAL / Diseases
MEDICAL / Evidence-Based Medicine
MEDICAL / Internal Medicine
Blood-brain barrier.
Nervous system --Diseases --Treatment.
Central Nervous System Agents.
Blood-Brain Barrier.
Drug Design.
Drug Delivery Systems.
Nervous System Diseases --therapy.
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