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Homeostatic Responses of the Enteric Cholinergic System in Stress and Enteritis
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Homeostatic Responses of the Enteric Cholinergic System in Stress and Enteritis. |
| 개인저자 | Pohl, Calvin Seneca. |
| 단체저자명 | Michigan State University. Comparative Medicine and Integrative Biology - Doctor of Philosophy. |
| 발행사항 | [S.l.]: Michigan State University., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 239 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-10B(E). Dissertation Abstract International |
| ISBN | 9780355968804 |
| 학위논문주기 | Thesis (Ph.D.)--Michigan State University, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Adam J. Moeser. |
| 요약 | Stressful, traumatic events are a well-recognized trigger leading to acute and chronic gastrointestinal (GI) disease like Irritable Bowel Syndrome (IBS) or Inflammatory Bowel Disease (IBD). Two major types of stress which are pervasive within th |
| 요약 | The enteric cholinergic nervous system is a major regulator of GI homeostasis with broad regulatory roles over epithelial barrier permeability, epithelial cell secretion, smooth muscle contraction and motility, and immune activation. Though a ro |
| 요약 | The objective of this dissertation was to determine if the enteric cholinergic nervous system contributed to GI disease under different types of environmental challenges including early life adversity, chronic stress and pathogen challenge. To a |
| 요약 | The results presented here demonstrate that different types of stressors differentially impact the enteric cholinergic system. Following early life adversity, we observed a persistent upregulation of the enteric cholinergic system, which predisp |
| 일반주제명 | Physiology. Immunology. Neurosciences. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
