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Electrophysiological and Optical Methods for Measuring Inputs to Individual Neurons

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서명/저자사항Electrophysiological and Optical Methods for Measuring Inputs to Individual Neurons.
개인저자Domnisoru, Cristina.
단체저자명Princeton University. Neuroscience.
발행사항[S.l.]: Princeton University., 2017.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2017.
형태사항191 p.
기본자료 저록Dissertation Abstracts International 79-05B(E).
Dissertation Abstract International
ISBN9780355480283
학위논문주기Thesis (Ph.D.)--Princeton University, 2017.
일반주기 Source: Dissertation Abstracts International, Volume: 79-05(E), Section: B.
Adviser: David Tank.
이용제한사항This item is not available from ProQuest Dissertations & Theses.
요약Understanding neural circuits requires being able to explain the mechanisms that result in the tuning functions of neurons during behavior. Such mechanistic explanations typically involve hypotheses about the tuning of both the postsynaptic neur
요약Here we first illustrate one strategy for model evaluation that exploits the fact that, in special cases, different circuit architectures proposed by different model families make distinct predictions about the membrane potential of neurons duri
요약We next develop strategies that build towards a general method for measuring the tuning of neurons and their inputs during behavior by using spine calcium imaging. By combining sparse GCaMP6s labeling, mouse screening for low brain motion, and a
일반주제명Nanoscience.
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