자료유형 | 학위논문 |
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서명/저자사항 | Models and Mechanisms to Evaluate Tissue Engineered Vascular Graft Stenosis. |
개인저자 | Clark, Elizabeth S. |
단체저자명 | The Ohio State University. Comparative and Veterinary Medicine. |
발행사항 | [S.l.]: The Ohio State University., 2017. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2017. |
형태사항 | 165 p. |
기본자료 저록 | Dissertation Abstracts International 79-10B(E). Dissertation Abstract International |
ISBN | 9780438092570 |
학위논문주기 | Thesis (Ph.D.)--The Ohio State University, 2017. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-10(E), Section: B.
Adviser: Christopher Breuer. |
요약 | Congenital heart disease represents the most common form of birth defect and is present in up to 1% of all live births. Of particular interest to our group is the treatment of single ventricle disease, specifically hypoplastic left heart syndrom |
요약 | The long-term goal of this project is to develop a second-generation composite vascular graft for use in children. The objective of this study is to elucidate the mechanism of TEVG neotissue formation in immunocompetent mice (Mus musculus) and c |
요약 | Previous research by our lab C57BL/6 mice has suggested that the transforming growth factor-beta (TGF-beta)/Smad2-3 pathway is involved in the development of TEVG stenosis. While the specific role of the TGF-beta pathway in the development of st |
일반주제명 | Biomedical engineering. Medicine. Pathology. Medical imaging. Biology. |
언어 | 영어 |
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