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Insulin Actions on Hippocampal Neurons
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Insulin Actions on Hippocampal Neurons. |
| 개인저자 | Maimaiti, Shaniya. |
| 단체저자명 | University of Kentucky. Pharmacology and Nutritional Sciences. |
| 발행사항 | [S.l.]: University of Kentucky., 2017. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2017. |
| 형태사항 | 164 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-11B(E). Dissertation Abstract International |
| ISBN | 9780438110649 |
| 학위논문주기 | Thesis (Ph.D.)--University of Kentucky, 2017. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-11(E), Section: B.
|
| 요약 | Aging is the main risk factor for cognitive decline. The hippocampus, a brain region critical for learning and memory formation, is especially vulnerable to normal and pathological age-related cognitive decline. Dysregulation of both insulin and |
| 요약 | We found that intranasal insulin improved memory in aged F344 rats. Young and aged F344 rats were treated with HumalogRTM, a short-acting insulin analog, or LevemirRTM, a long-acting insulin analog. The aged rats performed similar to young rats |
| 요약 | These results suggest that increasing brain insulin levels in aged rats may have improved memory by reducing the AHP and intracellular Ca2+concentrations. This study indicates a possible mechanism responsible for the beneficial effects of intran |
| 일반주제명 | Pharmacology. Neurosciences. Aging. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
