자료유형 | 학위논문 |
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서명/저자사항 | Microfabricated Sampling Probes for Monitoring Brain Chemistry at High Spatial and Temporal Resolution. |
개인저자 | Ngernsutivorakul, Thitaphat. |
단체저자명 | University of Michigan. Chemistry. |
발행사항 | [S.l.]: University of Michigan., 2018. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
형태사항 | 215 p. |
기본자료 저록 | Dissertation Abstracts International 79-12B(E). Dissertation Abstract International |
ISBN | 9780438125940 |
학위논문주기 | Thesis (Ph.D.)--University of Michigan, 2018. |
일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Robert T. Kennedy. |
요약 | Monitoring neurochemical dynamics has played a crucial role in elucidating brain function and related disorders. An essential approach for monitoring neurochemicals is to couple sampling probes to analytical measurements |
요약 | Conventional sampling probes were handmade and have several disadvantages, including large sizes (over 220 mum in diameter) and limited design flexibility. To address these disadvantages, we have used microfabrication to manufacture sampling pro |
요약 | Furthermore, we have continued the development of a microfabricated push-pull probe. We enhanced functionality of the probe by integrating an additional channel into the probe for chemical delivery. Further, we demonstrated that the probe can fe |
요약 | This collection of work illustrates that development of the microfabricated sampling probes and their compatible microfluidic systems are highly beneficial for studying brain chemistry. The integrated miniaturized analytical technology can poten |
일반주제명 | Organic chemistry. Neurosciences. |
언어 | 영어 |
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