상세정보
Export to Refworks부가기능
Case Studies of Cryptic Proteins Contributing to Shape Change in Eosinophils: Workflows to Investigate STAT3, LOCGEF and NHSL2
상세 프로파일
| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Case Studies of Cryptic Proteins Contributing to Shape Change in Eosinophils: Workflows to Investigate STAT3, LOCGEF and NHSL2. |
| 개인저자 | Turton, Keren B. |
| 단체저자명 | The University of Wisconsin - Madison. Biomolecular Chemistry. |
| 발행사항 | [S.l.]: The University of Wisconsin - Madison., 2018. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2018. |
| 형태사항 | 263 p. |
| 기본자료 저록 | Dissertation Abstracts International 79-12B(E). Dissertation Abstract International |
| ISBN | 9780438271593 |
| 학위논문주기 | Thesis (Ph.D.)--The University of Wisconsin - Madison, 2018. |
| 일반주기 |
Source: Dissertation Abstracts International, Volume: 79-12(E), Section: B.
Adviser: Deane F. Mosher. |
| 요약 | Following interleukin-5 stimulation, eosinophils rapidly become acorn-shaped. The bi-lobed nucleus is propelled to the cone of the acorn, termed the "nucleopod". By integrating eosinophil immunostaining with (phospho)proteomics data |
| 요약 | Signal transducer and activator of transcription 3 (STAT3) is an important regulator of transcription in activated leukocytes. An unexpected STAT3 isoform peptide, lacking a single residue (Ser701) led to the questions, what are the relative pro |
| 요약 | We describe the "LOCGEFs", a set of leukocyte-specific spliceforms of ARHGEF18, a guanine nucleotide exchange factor. These proteins were discovered because the proteomics dataset included peptides mapping to a protein annotated as LOC100996504. |
| 요약 | Nance-Horan Syndrome-like protein 2 (NHSL2) was one of the most profoundly altered proteins after IL5 treatment: within 5 minutes, the fold-phosphorylation at 4 sites increased dramatically. Nearly nothing is published about this protein, so we |
| 일반주제명 | Biochemistry. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
