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Recollection Precision: Neural Mechanisms and Modulation via Network-Targeted Brain Stimulation
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| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Recollection Precision: Neural Mechanisms and Modulation via Network-Targeted Brain Stimulation. |
| 개인저자 | Nilakantan, Aneesha Sekhar. |
| 단체저자명 | Northwestern University. Interdepartmental Neuroscience Program (NUIN). |
| 발행사항 | [S.l.]: Northwestern University., 2019. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2019. |
| 형태사항 | 106 p. |
| 기본자료 저록 | Dissertations Abstracts International 81-04B. Dissertation Abstract International |
| ISBN | 9781088317976 |
| 학위논문주기 | Thesis (Ph.D.)--Northwestern University, 2019. |
| 일반주기 |
Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
Advisor: Voss, Joel L |
| 이용제한사항 | This item must not be sold to any third party vendors.This item must not be added to any third party search indexes. |
| 요약 | Episodic memory provides a means by which we are able to reflect on the past, make decisions about the future, and form a learned identity. Even subtle changes to our memory can have a detrimental impact on our daily lives. Memory declines as we age, and clinically salient impairment is one of the defining symptoms of amnestic mild cognitive impairment and diagnosis of dementia due to Alzheimer's disease. As a result, decades of research have been dedicated to unpacking the mechanisms by which the brain, specifically the hippocampus, supports the formation and retrieval of different forms of memory. However, recollection memory is typically tested using all-or-nothing measures of general success that fail to capture the quality and details (precision) of the memory recalled. Here, I present a series of experiments combing noninvasive neuroimaging techniques with behavioral paradigms that utilize novel analysis approaches, in order to characterize the precision of recollection. Results from these experiments demonstrate that recollection precision is critically dependent on the hippocampus, relies on a distributed cortical network, is a sensitive measure that selectively captures impairment due to age, and can be improved via noninvasive stimulation. |
| 일반주제명 | Neurosciences. Cognitive psychology. Aging. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
