상세정보
Export to Refworks부가기능
Advancements in Nickel-Catalyzed Cross-Electrophile Coupling
상세 프로파일
| 자료유형 | 학위논문 |
|---|---|
| 서명/저자사항 | Advancements in Nickel-Catalyzed Cross-Electrophile Coupling. |
| 개인저자 | Johnson, Keywan A. |
| 단체저자명 | The University of Wisconsin - Madison. Chemistry. |
| 발행사항 | [S.l.]: The University of Wisconsin - Madison., 2019. |
| 발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2019. |
| 형태사항 | 180 p. |
| 기본자료 저록 | Dissertations Abstracts International 81-03B. Dissertation Abstract International |
| ISBN | 9781085652537 |
| 학위논문주기 | Thesis (Ph.D.)--The University of Wisconsin - Madison, 2019. |
| 일반주기 |
Source: Dissertations Abstracts International, Volume: 81-03, Section: B.
Advisor: Weix, Daniel J. |
| 이용제한사항 | This item must not be sold to any third party vendors.This item must not be added to any third party search indexes. |
| 요약 | In this thesis, the extension of cross-electrophile coupling to engage vinyl halides, organic chlorides, and dihalides for cyclization will be described in detail.Chapter 1 will provide an introduction to cross-electrophile coupling and the current state of the art for these transformations.Chapter 2 describes the development of improved coupling conditions for the nickel-catalyzed cross-electrophile coupling of vinyl halides with alkyl halides. The application of these conditions to aryl-alkyl coupling, substrate scope and limitations, and preliminary mechanistic insights are also discussed.Chapter 3 describes studies performed for the coupling of aryl and alkyl chlorides. The effects of a dual ligand system on reaction selectivity, as well as implications of dimethoxyethane and diglyme nickel precatalysts are also conferred.Chapter 4 provides a survey of macrocyclization methodologies and details the application of cross-electrophile coupling to the synthesis of macrocyclic rings. Efforts towards the total synthesis of (짹)-Recifeiolide are also discussed. |
| 일반주제명 | Organic chemistry. Chemistry. |
| 언어 | 영어 |
| 바로가기 | 
: 이 자료의 원문은 한국교육학술정보원에서 제공합니다. |
