자료유형 | 학위논문 |
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서명/저자사항 | Development of Parenteral Drugs for the Treatment of Seizure Emergencies. |
개인저자 | Vuu, Irene. |
단체저자명 | University of Minnesota. Experimental & Clinical Pharmacology. |
발행사항 | [S.l.]: University of Minnesota., 2019. |
발행사항 | Ann Arbor: ProQuest Dissertations & Theses, 2019. |
형태사항 | 233 p. |
기본자료 저록 | Dissertations Abstracts International 81-04B. Dissertation Abstract International |
ISBN | 9781392522974 |
학위논문주기 | Thesis (Ph.D.)--University of Minnesota, 2019. |
일반주기 |
Source: Dissertations Abstracts International, Volume: 81-04, Section: B.
Advisor: Cloyd, James C |
이용제한사항 | This item must not be sold to any third party vendors.This item must not be added to any third party search indexes. |
요약 | The overall objective of my dissertation is to develop alternative therapies for seizure emergencies. Status epilepticus is a condition defined as a convulsive seizure lasting more than 5 minutes and is considered a seizure emergency due to the increased risk for neuronal damage and mortality (Trinka et al. 2015). Although relatively effective, first-line therapy fails to terminate status epilepticus in 26-57% of cases, leading to increased risk of seizure refractoriness and use of second- and third-line therapies that may increase the risk of systemic complications and mortality (Treiman et al. 1998 |
일반주제명 | Pharmaceutical sciences. |
언어 | 영어 |
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