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Antioxidant Supplementation to Alleviate the Negative Effects of Heat and Oxidative Stress on Performance and Health of Nursery and Growing Pigs

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서명/저자사항Antioxidant Supplementation to Alleviate the Negative Effects of Heat and Oxidative Stress on Performance and Health of Nursery and Growing Pigs.
개인저자Silva Guillen, Ysenia Victoria.
단체저자명North Carolina State University.
발행사항[S.l.]: North Carolina State University., 2019.
발행사항Ann Arbor: ProQuest Dissertations & Theses, 2019.
형태사항190 p.
기본자료 저록Dissertations Abstracts International 81-05B.
Dissertation Abstract International
ISBN9781392551585
학위논문주기Thesis (Ph.D.)--North Carolina State University, 2019.
일반주기 Source: Dissertations Abstracts International, Volume: 81-05, Section: B.
Advisor: Lanzas, Cristina
이용제한사항This item must not be sold to any third party vendors.
요약The present dissertation evaluated the supplementation of vitamin E, polyphenols or phytogenics in feed or drinking water on growth performance, immune and oxidative status in growing pigs housed under heat stress and in weaned piglets fed peroxidized oil diets. In study 1 (Chapter II) the impact of antioxidants on growth, intestinal morphology, hematology indices, immune and oxidative status in growing pigs housed under heat stress was evaluated in 2 replicated experiments. In each experiment, 64 crossbred pigs were used, with an initial body weight (BW) of 50.7짹3.8 kg and 43.9짹 3.6 and age of 13-weeks and 12-weeks old for each experiment, respectively. Individually housed pigs were assigned within weight blocks and sex to a 2 x 4 factorial arrangement consisting of 2 environments (thermo-neutral (21.2째C) or heat-stressed (30.9째C)) and 4 supplementation treatments (control, control+vitamin E in water, control+vitamin E in feed, and control+polyphenols in feed). Heat stress reduced growth, but no effects of supplementation were found. Intestinal morphology was not affected by heat stress or supplementation or their interaction. Intestinal cellular proliferation was increased in pigs supplemented with vitamin E in feed and water during heat stress. Serum and liver vitamin E were increased with vitamin E supplementation, especially when supplemented in water. Serum malondialdehyde (MDA), an oxidative stress marker, was greater with antioxidant supplementation compared with control, and on d 2 vs. d 28. MDA in ileal mucosa was increased when using dietary vitamin E and polyphenols. Immune status evaluated using serum cytokines was not impacted by heat stress or supplementation. Red blood cells, hemoglobin and hematocrit percentage were reduced by heat stress when measured on d 28. White blood cells, platelets, and monocyte counts were reduced on d 28 vs. d 2. In the study 2 (Chapter III), the effects of dietary vitamin E and polyphenols on growth, and immune and oxidative status in weaned piglets was evaluated. Pigs (n=192
일반주제명Livestock.
Animal sciences.
언어영어
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